Found 14 matching trials
Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases PHASE2 Brain metastases are the most common brain tumors in adults. It is estimate...
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National Taiwan University Hospital
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Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC NA WBRT (whole-brain radiation therapy) exhibits poor tumor control and decrea...
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Active Not Recruiting
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SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC PHASE3 This phase III trial compares the effect of stereotactic radiosurgery and w...
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SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases PHASE2 The goal of this phase II randomized trial is to determine if Stereotactic ...
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Multiple Locations
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Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy PHASE2 This clinical trial aims to evaluate the efficacy of early intervention wit...
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Multiple Locations
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Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases PHASE3 This is a phase 3, randomized, controlled clinical trial comparing two brai...
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The First Affiliated Hospital of Chongqing Medical University
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WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases PHASE1 This study aims to evaluate the safety and efficacy of hippocampal-sparing ...
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Fudan University Shanghai Cancer Center
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HA-WBRT-SIB for Brain Metastasis of Lung Cancer PHASE2 Patients with lung cancer and brain metastases undergo HA-WBRT-SIB using im...
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National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciecnces and Peking Union Medical College
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Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases PHASE3 This randomized phase III trial compares memantine hydrochloride and whole-...
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Lewis and Faye Manderson Cancer Center
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HA-WBRT vs SRS in Patients With Multiple Brain Metastases PHASE3 This study compares the effectiveness and safety of two radiation treatment...
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Medical University Innsbruck
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